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Description

The half-life of retatrutide is approximately 6 days

Curr Drug Metab (2011) 12:66778

Originally it was approved by the Food and Drug Administration (FDA) along with diet and exercise to lower blood glucose levels in adults with type 2 diabetes (T2DM)

Hsieh, T.-h

Jimenez-Solem E, Rasmussen MH, Christensen M, Knop FK (2010) Dulaglutide, a long-acting GLP-1 analog fused with an Fc antibody fragment for the potential treatment of type 2 diabetes

Initially approved to treat diabetes, glucagon-like peptide-1 (GLP-1) drugs are being heralded to address obesity and, more recently, obstructive sleep apnea (OSA)